Thursday, 8 January 2015

Alcohol abuse

Evidence Based Reports

Motivational interviewing for alcohol misuse in young adults (2014)[Cochrane Library] NEW

Anticonvulsants for alcohol dependence (2014)[Cochrane Library] NEW

Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users (2014)[Cochrane Library] NEW

Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings (2014)[HTA] NEW

Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol. (2013) [Cochrane Library]

Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials. (2013) [DARE]

Meta-analysis of supplemental treatment for depressive and anxiety disorders in patients being treated for alcohol dependence. (2012) [DARE]

Acamprosate for alcohol dependence: a sex-specific meta-analysis based on individual patient data. (2012) [DARE]

Exercise and non-alcoholic fatty liver disease: a systematic review and meta-analysis. (2012) [DARE]

Alcohol misuse (2011)[Clinical Evidence] subscription required

Propylthiouracil for alcoholic liver disease (2011)[CochraneLibrary]

Benzodiazepines for alcohol withdrawal (2010)[Cochrane Library]

Acamprosate for alcohol dependence (2010)[Cochrane Library]

Anticonvulsants for alcohol withdrawal (2010)[Cochrane Library]

Gamma-hydroxybutyrate (GHB) for treatment of alcohol withdrawal and prevention of relapses (2010)[Cochrane Library]

Pharmacologic Interventions for Pregnant Women Enrolled in Alcohol Treatment (2010)[Cochrane Library]

Acupuncture for alcohol dependence: a systematic review (2010)[DARE]

Interventions for reducing adolescent alcohol abuse: a meta-analytic review (2010) [DARE]

Cost-effectiveness of screening for unhealthy alcohol use with %carbohydrate deficient transferrin: results from a literature-based decision analytic computer model (2010)[NHS EED]

The cost effectiveness of naltrexone added to cognitive-behavioral therapy in the treatment of alcohol dependence (2010)[NHS EED]

Clinical Guidelines

Nalmefene for reducing alcohol consumption in people with alcohol dependence (2014)[NICE Technology Appraisals] NEW

Alcohol dependence and harmful alcohol use quality standard (2011)[NICE]

Alcohol - problem drinking (2011)[CKS]

The management of harmful drinking and alcohol dependence in primary care (2009)[SIGN]

Recent articles in core journals

Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis (2014)[EvidenceUpdates] NEW

Web-based alcohol screening and brief intervention for university students: a randomized trial (2014)[JAMA] NEW

Effects of minimum unit pricing for alcohol on different income and socioeconomic groups: a modelling study (2014)[EvidenceUpdates] NEW

Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. (2013) [JAMA]

Concurrent naltrexone and prolonged exposure therapy for patients with comorbid alcohol dependence and PTSD: a randomized clinical trial. (2013) [JAMA]

Influence of serum sodium on MELD-based survival prediction in alcoholic hepatitis.(2011)[EvidenceUpdates]

Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: meta-analysis of individual patient data.(2011)[EvidenceUpdates]

Early liver transplantation for severe alcoholic hepatitis.(2011)[NEJM]

Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis.(2011)[NEJM]

The spread of alcohol consumption behavior in a large social network. (2009)[Annals of Internal Medicine]

Effectiveness and cost-effectiveness of a stepped care intervention for alcohol use disorders in primary care: pilot study (2010)[EvidenceUpdates]

Effects of a brief intervention for reducing violence and alcohol misuse among adolescents: a randomized controlled trial. (2010)[JAMA]

A double-blind, placebo-controlled trial combining sertraline and naltrexone for treating co-occurring depression and alcohol dependence (2010)[EvidenceUpdates]

Interventions for reducing adolescent alcohol abuse: a meta-analytic review (2010)[EvidenceUpdates]


Alcoholism (2014)[eMedicine] updated

Alcoholic Fatty Liver (2014)[eMedicine] updated

Alcohol and Substance Abuse Evaluation (2014)[eMedicine] updated

Alcoholic Ketoacidosis (2014)[eMedicine] updated

Fetal Alcohol Syndrome (2013)[Mentor]

Alcohol Related Problems (2012)[Mentor]

Fetal Alcohol Syndrome (2012)[eMedicine]

Alcoholism and Alcohol Abuse - Management (2011) [Mentor]

Clinical Queries

What contraception can be used by a 39 year old woman who smokes between 20 and 40 cigarettes per day, has undergone a liver transplant as a result of alcoholic liver disease, and who is currently taking steroids and tacrolimus? (2013) [FSRH]

With patients with alcohol dependence, does acamprosate plus usual care compared to usual care (ITT analysis) reduce alcohol dependence, mortality or hospitalisation rates? (2009)[TRIPAnswers]

How useful is carbohydrate deficient transferrin (CDT) as a marker for alcohol abuse? what are its limitations? (2009)[TRIPAnswers]

Is it safe to prescribe oral antifungals for a fungal nail infection, to a gentleman who drinks excessive alcohol with a raised GGT( 107), but normal LFTs? (2008)[TRIPAnswers]

Patient Information

Alcohol misuse (2013)[NHS Choices]

Sensible Drinking (2013)[BUPA]

Alcohol Detoxification (2010)[Patient UK]


1. If you are a Welsh Primary Care Professional with a clinical query send it to ATTRACT online or email us at or call 01495 332343.
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