Menorrhagia

Evidence Based Reports

Endometrial resection/ablation as effective as hysterectomy for heavy menstrual bleeding (2014)[Cochrane PEARLS] NEW

First- versus second-generation endometrial ablation devices for treatment of menorrhagia: a systematic review, meta-analysis and appraisal of economic evaluations (2014)[DARE] NEW

Menorrhagia (2012) [Clinical Evidence] subscription required

Surgery versus medical therapy for heavy menstrual bleeding (2010)[Cochrane Library]

Hysterectomy, endometrial destruction, and levonorgestrel releasing intrauterine system (Mirena) for heavy menstrual bleeding: systematic review and meta-analysis of data from individual patients (2010) [Dare]

Endometrial resection / ablation techniques for heavy menstrual bleeding (2009)[Cochrane Library]

Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding (2009)[Cochrane Libary]

Oral contraceptive pill for heavy menstrual bleeding (2010)[Cochrane Library]

Cyclical progestogens for heavy menstrual bleeding (2008)[Cochrane Library]

Danazol for heavy menstrual bleeding (2007) [Cochrane Library]

Nonsteroidal anti-inflammatory drugs for heavy menstrual bleeding (2007) [Cochrane Library]

Clinical Guidelines

Menorrhagia(2012)[CKS]

Recent articles in core journals

Quality of life and costs of levonorgestrel-releasing intrauterine system or hysterectomy in the treatment of menorrhagia: a 10-year randomized controlled trial (2014)[EvidenceUpdates] NEW

Levonorgestrel intrauterine system versus medical therapy for menorrhagia (2013) [NEJM]

Ten-year follow-up of a randomised controlled trial comparing bipolar endometrial ablation with balloon ablation for heavy menstrual bleeding.(2013)[EvidenceUpdates]

Nonsurgical management of heavy menstrual bleeding: a systematic review.(2013)[EvidenceUpdates]

Second generation endometrial ablation techniques for heavy menstrual bleeding: network meta-analysis.(2012)(BMJ)

Five-year follow-up after comparing bipolar endometrial ablation with hydrothermablation for menorrhagia. (2012)[EvidenceUpdates]

A dose-response study of a novel, oral tranexamic formulation for heavy menstrual bleeding.(2011)[EvidenceUpdates]

Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: a randomized controlled trial. (2010)[EvidenceUpdates]

Clinical outcomes from a randomised comparison of Microwave Endometrial Ablation with Thermal Balloon endometrial ablation for the treatment of heavy menstrual bleeding (2009)[EvidenceUpdates]

Levonorgestrel-releasing intrauterine system and endometrial ablation in heavy menstrual bleeding: a systematic review and meta-analysis (2009)[EvidenceUpdates]

The effect of hysterectomy or levonorgestrel-releasing intrauterine system on sexual functioning among women with menorrhagia: a 5-year randomised controlled trial (2007) [BJOG]

eTextbooks

Menorrhagia (2014)[eMedicine] updated

Menorrhagia (2009) [GPNotebook]

Clinical Queries

Is there a minimum age at which combined oral contraceptives (COC) should be considered solely for management of heavy menstrual bleeding and dysmenorrhoea? (2014) [FSRH] NEW

Can women with von Willebrand disease (vWD) use the levonorgestrel-releasing intrauterine system (LNG-IUS) or contraceptive implant for heavy menstrual bleeding? (2014)[FSRH] NEW

Can the levonorgestrel intrauterine system (LNG-IUS) be safely used by women in their 50s to control heavy menstrual bleeding if they have a past history of subarachnoid haemorrhage? (2114)[FSRH] NEW

Can a patient with trimethylaminuria (TMAU) use a levonorgestrel intrauterine system (LNG-IUS) for contraception and to control menorrhagia without it exacerbating her symptoms? (2013) [FSRH]

Can a woman with secondary Sjögren’s Syndrome with a rheumatoid overlap and heavy menstrual bleeding safely use the levonorgestrel-releasing intrauterine system (LNG-IUS)? (2012) [FSRH]

Is tranexamic acid better than or as effective as mefenamic acid in managing menorrhagia? (2008)[ATTRACT]

Is there an increased risk of a DVT using tranexamic acid for menorrhagia, especially on long haul flights? (2008) [TRIPAnswers]

Patient Information

Menorrhagia (2014) [Patient UK] updated

Intrauterine system (IUS) for heavy periods. (2014) [BUPA] updated

Periods, heavy (menorrhagia) (2012) [NHS Choices]


Important

1. If you are a Welsh Primary Care Professional with a clinical query send it to ATTRACT online or email us at questions@attract.wales.nhs.uk or call 01495 332343.
2. If you would like to comment on this CME topic, or suggest a new topic for ATTRACTcme, go to the comments hyperlink below.