Friday, 14 February 2014


Evidence Based Reports

Apremilast for psoriasis (2013) [ National Horizon Scanning Centre] NEW

Dimethyl fumarate for plaque psoriasis (2013) [National Horizon Scanning Centre] NEW

Ustekinumab (Stelara) for plaque psoriasis in adolescents (2013) [National Horizon Scanning Centre] NEW

Biologic and Nonbiologic Systemic Agents and Phototherapy for Treatment of Chronic Plaque Psoriasis (2012) [AHRQ] [Summary document] NEW

Tofacitinib for moderate to severe chronic plaque psoriasis – second line (2012) [National Horizon Scanning Centre] NEW

Secukinumab for plaque psoriasis (2012) [National Horizon Scanning Centre] NEW

Infliximab versus Methotrexate, Etanercept, Adalimumab, and Ustekinumab for Plaque Psoriasis: A Review of the Comparative Clinical Efficacy, Safety and Cost Effectiveness (2012)[CADTH] NEW

Efficacy of biologics in the treatment of moderate to severe psoriasis: a network meta-analysis of randomized controlled trials (2012)[
Association between biologic therapies for chronic plaque psoriasis and cardiovascular events: a meta-analysis of randomized controlled trials (2011) [DARE]

Ustekinumab for the treatment of adults with moderate to severe psoriasis (2009)[NICE]

Etanercept and efalizumab for the treatment of adults with psoriasis (2006)[NICE]

Topical treatments for chronic plaque psoriasis (2011)[Cochrane] updated

Infliximab for the treatment of adults with psoriasis (2008)[NICE]

Adalimumab for the treatment of adults with psoriasis (2008)[NICE]

Safety and efficacy of alefacept, efalizumab, etanercept and infliximab in treating moderate to severe plaque psoriasis: a meta-analysis of randomized controlled trials (2008)[DARE]

Psoriasis (chronic plaque)(2007)[Clinical Evidence]

Clinical Guidelines
Psoriasis:The assessment and management of psoriasis (2012)[NICE] NEW

Psoriasis(2012)[CKS] updated

Diagnosis and management of psoriasis and psoriatic arthritis in adults(2010)[SIGN]

British Association of Dermatologists’ guidelines for biologic interventions for psoriasis (2009)[British Association of Dermatologists]

Recent articles in core journals

Effective and sustainable biologic treatment of psoriasis: what can we learn from new clinical data? (2012) [J Eur Acad Dermatol Venereol] NEW

Adherence to topical treatment in psoriasis: a systematic literature review (2012) [J Eur Acad Dermatol Venereol] NEW

Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis (2012) [NEJM]NEW

Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis (2012)[NEJM]NEW

A 52-week trial comparing briakinumab with methotrexate in patients with psoriasis (2011)[NEJM]

Comparison of two etanercept regimens for treatment of psoriasis and psoriatic arthritis: PRESTA randomised double blind multicentre trial (2010)[BMJ]

Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis (2010)[NEJM]

Efficacy and safety of combination Acitretin and Pioglitazone therapy in patients with moderate to severe chronic plaque-type psoriasis: a randomized, double-blind, placebo-controlled clinical trial (2009)[Arch Dermatol]

Incidence and clinical predictors of psoriatic arthritis in patients with psoriasis: a population-based study(2009)[Arthritis Rheum]

A new scalp formulation of calcipotriene plus betamethasone compared with its active ingredients and the vehicle in the treatment of scalp psoriasis: a randomized, double-blind, controlled trial (2008)[J Am Acad Dermatol]

Etanercept treatment for children and adolescents with plaque psoriasis (2008)[NEJM]


Psoriasis (2014)[eMedicine] updated

Plaque Psoriasis (2013)[eMedicine] updated

Psoriasis, Pustular (2013)[eMedicine] updated

Psoriasis of Hands and Feet (2013)[Mentor] updated

Chronic Plaque Psoriasis (2012)[Mentor] updated

Guttate Psoriasis (2011)[Mentor]

Generalised Pustular Psoriasis (2011)[Mentor]

Erythrodermic Psoriasis (2011)[Mentor]

Clinical Queries

What is evidence for use of low dose naltrexone in psoriasis.? It would be unlicenced use - what information would I need to share with patient and can I prescribe on nhs? (2012) [ATTRACT] NEW

Cigarette smoking is known to reduce the symptoms and severity of psoriasis. Can nicotine replacement therapy have similar benefits? (2012)[ATTRACT]NEW

What is the evidence for neem oil in scalp psoriasis? (2010)[ATTRACT]

Is there any evidence that propranolol makes psoriasis worse? (2008)[ATTRACT]

Patient Information

Treatments for Moderate or Severe Psoriasis (2013)[British Association of Dermatologists] updated

Topical Treatments for Psoriasis (2013)[British Association of Dermatologists] updated

Psoriasis (2013)[NHS Choices] updated

Psoriasis – an Overview (2012)[British Association of Dermatologists] updated

Psoriasis (2012)[Patient UK] updated

Coal Tar for Psoriasis (2012)[Patient UK] updated

Vitamin D Analogues for Psoriasis (2012)[Patient UK] updated

Psoriasis (2012)[BUPA] updated


1. If you are a Welsh Primary Care Professional with a clinical query send it to ATTRACT online or email us at or call 01495 332343.
2. If you would like to comment on this CME topic, or suggest a new topic for ATTRACTcme, go to the comments hyperlink below.

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