Newer oral anticoagulants (2013) [WeMeRec] NEW
Rivaroxaban for treating pulmonary embolism and preventing recurrent venous thromboembolism (2013) [NICE] NEW
Warfarin initiation nomograms for venous thromboembolism (2013)[Cochrane] NEW
Once versus twice daily low molecular weight heparin for the initial treatment of venous thromboembolism (2013)[Cochrane] NEW
Antiplatelet and anticoagulation for patients with prosthetic heart valves(2013)[Cochrane] updated
Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non–ST Elevation Myocardial Infarction (2013)[AHRQ][Executive Summary] NEW
Tinzaparin versus Dalteparin or Enoxaparin for the Treatment of Venous Thromboembolism in Adults: Safety and Guidelines (2013)[CADTH] NEW
Low Molecular Weight Heparins Versus Unfractionated Heparin for Thromboprophylaxis in Surgery, Cancer and General Medicine: A Review of the Cost-effectiveness and Safety (2013)[CADTH] NEW
Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism (2012) [NICE] NEW
Apixaban for the prevention of venous thromboembolism after total hip or knee replacement in adults (2012)[NICE] NEW
Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment (2012)[Cochrane] NEW
Thrombophilia testing for prevention of recurrent venous thromboembolism(2012)[Cochrane] updated
Comparative effectiveness of warfarin and new oral anticoagulants for the management of atrial fibrillation and venous thromboembolism: a systematic review (2012)[DARE] NEW
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2011)[Cochrane] NEW
Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed arterial origin (2011) [Cochrane] updated
Low molecular weight heparin versus unfractionated heparin for perioperative thromboprophylaxis in patients with cancer (2011) [Cochrane]
Anticoagulation for the long-term treatment of venous thromboembolism in patients with cancer (2011)[Cochrane]
Anticoagulation for the initial treatment of venous thromboembolism in patients with cancer (2011)[Cochrane]
Oral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation (2010)[Cochrane]
Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm (2010)[Cochrane] NEW
Fixed dose subcutaneous low molecular weight heparins versus adjusted dose unfractionated heparin for venous thromboembolism (2010)[Cochrane]
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of venous thromboembolism following total hip or knee replacement (2010)[Cochrane]
Parenteral anticoagulation for prolonging survival in patients with cancer who have no other indication for anticoagulation (2010) [Cochrane] updated
Systematic review: case-fatality rates of recurrent venous thromboembolism and major bleeding events among patients treated for venous thromboembolism (2010)[DARE]
Dabigatran etexilate (Pradaxa) for secondary prevention of venous thromboembolism (VTE)(2010)[National Horizon Scanning Centre]
Anticoagulation for Venous Thromboembolism (2010)[theNNT]
Oral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation (2010) [Cochrane]
Rivaroxaban for the prevention of venous thromboembolism after total hip or total knee replacement in adults(2009)[NICE]
Subcutaneous unfractionated heparin for the initial treatment of venous thromboembolism(2009)[Cochrane]
Interventions for preventing venous thromboembolism following abdominal aortic surgery(2009)[Cochrane]
Aspirin or anticoagulants for treating recurrent miscarriage in women without antiphospholipid syndrome(2008)[Cochrane]
Anticoagulants for preventing recurrence following presumed non-cardioembolic ischaemic stroke or transient ischaemic attack (2008)[Cochrane]
Self-monitoring and self-management of oral anticoagulation (2008)[Cochrane]
Idrabiotaparinux for the treatment of DVT and/or PE and secondary prevention of venous thromboembolism (2008)[National Horizon Scanning Centre]
Dabigatran etexilate (Pradaxa) for acute symptomatic venous thromboembolism (2008)[National Horizon Scanning Centre]
AVE-5026 for the prevention of venous thromboembolism in patients at risk (2008)[National Horizon Scanning Centre]
Anticoagulants for acute ischaemic stroke (2008)[Cochrane]
Anticoagulants versus non-steroidal anti-inflammatories or placebo for treatment of venous thromboembolism (2008)[Cochrane]
Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke (2008)[Cochrane]
Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-leg immobilization (2008)[Cochrane]
Anticoagulants versus non-steroidal anti-inflammatories or placebo for treatment of venous thromboembolism (2008) [Cochrane]
Oral anticoagulants versus antiplatelet therapy for preventing stroke in patients with non-valvular atrial fibrillation and no history of stroke or transient ischemic attacks (2006) [Cochrane]
Monitoring anticoagulant therapy in primary care (2007) [WeMeRec]
Oral anticoagulants for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks (2004) [Cochrane]
Clinical Guidelines
Anticoagulation (2014)[Map of Medicine] updated
Oral anticoagulation (2013)[CKS] updated
Venous thromboembolic diseases: the management of venous thromboembolic diseases and the role of thrombophilia testing (2012)[NICE] NEW
Effects on routine coagulation screens and assessment of anticoagulant intensity in patients taking oral dabigatran or rivaroxaban: Guidance from the British Committee for Standards in Haematology (2012) [BSCH] NEW
Guidelines on the diagnosis and management of heparin induced thrombocytopenia: second edition (2012) [BSCH] NEW
Guidelines on the investigation and management of venous thrombosis at unusual sites (2012)[BSCH] NEW
Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies (2012)[BSCH] NEW
Guideline on the investigation, management and prevention of venous thrombosis in children (2011)[BSCH]
Guidelines on oral anticoagulation with warfarin – fourth edition (2011)[BSCH]
Venous Thromboembolism and Hormone Replacement Therapy (2011) [RCOG]
Prevention and management of venous thromboembolism (2010)[SIGN]
Venous thromboembolism:reducing the risk (2010)[NICE]
Guidelines for the management of anticoagulant and antiplatelet therapy in patients undergoing endoscopic procedures (2008)[British Soc Gastroenterology]
eTextbooks
Oral Anticoagulants (2013)[Mentor] updated
Starting patients on anticoagulants: how to do it (2007) [BMJ Learning]
Maintaining patients on anticoagulants: how to do it (2007) [BMJ Learning]
Recent articles in core journals
Dabigatran versus warfarin in patients with mechanical heart valves (2013)[NEJM] NEW
Sustained impact of anticoagulant control achieved in an anticoagulation management service after transfer of management to the primary care physician (2012) [Pharmacotherapy] NEW
Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomised controlled trial. (2011)[Lancet]
Duration and magnitude of the postoperative risk of venous thromboembolism in middle aged women: prospective cohort study (2009)[BMJ]
Meta-analysis: travel and risk for venous thromboembolism (2009)[Annals of Internal Medicine]
Risks and benefits of oral anticoagulation compared with clopidogrel plus aspirin in patients with atrial fibrillation according to stroke risk: the atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events (ACTIVE-W).(2008)[Stroke]
Combined aspirin-oral anticoagulant therapy compared with oral anticoagulant therapy alone among patients at risk for cardiovascular disease: a meta-analysis of randomized trials(2008)[Arch Intern Med]
Oral anticoagulant and antiplatelet therapy and peripheral arterial disease (2007)[NEJM]
Clinical Queries
Is there any consensus as to whetherthe dose of warfarin should be adjusted prior to starting a course of antibiotics or is it suffice to check the INR after the course is completed? (2013)[ATTRACT] NEW
Is it safe for a woman with a history of venous thromboembolism (VTE), currently being treated with anticoagulants, to use two desogestrel pills a day to remain amenorrhoeic? (2013) [FSRH] NEW
Is there any consensus as to how antimalarials should be used when patients are on warfarin (2012) [ATTRACT] NEW
Can a woman who has a heart valve replacement who is going to need warfarin for life use the progestogen-only implant? (2011)[FSRH]
How safe is it to perform a 'steroid injection' into a shoulder joint in someone taking Warfarin (2011)[ATTRACT]
Patient Information
Anticoagulant Medicines (2013) [NHS Choices] updated
Important
1. If you are a Welsh Primary Care Professional with a clinical query send it to ATTRACT online or email us at questions@attract.wales.nhs.uk or call 01495 332343.
2. If you would like to comment on this CME topic, or suggest a new topic for ATTRACTcme, go to the comments hyperlink below.http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001100.pub3/abstract
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